ED Therapy Trimix Specialist

Texas Anti-Aging Medicine Institute

Anti-Aging Specialist located in Plano, TX

For Healthier, Stronger and Harder Penis

ED Therapy Trimix

What is Trimix?

Trimix is a compounded combination of three drugs that is traditionally used for erectile dysfunction. The three drugs are alprostadil (prostaglandin), phentolamine and papaverine. The combination is usually injected prior to intercourse and is intended to cause vasodilation (expansion of the blood vessels) to help with erectile dysfunction.

Papaverinevasodilator

Phentolaminealpha blocker

Alprostadilprostaglandin

How to use Trimix

1. Wait 3 days between injections.

2. Do not inject more than 6 times a month.

3. Keep mixture refrigerated, as effectiveness will decrease if left at higher temperatures.

4. Your initial dose is 10 units on an insulin syringe. Wait 3 days before increasing dosage. Increase by 5 units until a satisfactory dose is reached. The maximum dose is 50 units. Do not be discouraged by a poor result with the first few injections, as the initial dose has been kept low to avoid a prolonged and painful erection (priapism).

5. Return to the office in 1 month for an interval evaluation and bring this worksheet. This is to be sure that you are not experiencing any difficulty and to check for scarring at the injection sites.

6. If you have any questions regarding the above instructions, please do not hesitate to call.

7. If your erection lasts longer than 1½ hours, you may take Sudafed if you are not on any high blood pressure medication, 60 mg orally (available without a prescription), apply an ice pack, and wait another hour. If the erection is still persistent please go to the Emergency Room immediately.

 

WORKSHEET

Date Dose Side Injected

     

 

 

TRIMIX SELF-INJECTION PROCEDURE

MAJOR STEPS

1. GETTING SET UP

2. PREPARE THE SYRINGE

3. SELECT AND PREPARE THE SITE FOR INJECTION

4. INJECT TRIMIX AND APPLY COMPRESSION

 

DETAILED PROCEDURE

Step 1: GETTING SET UP

a. Proper hygiene is important. Wash your hands and keep the penis clean.

b. Assemble the following:

  • Bottle of Trimix
  • Alcohol pad
  • Syringe

c. Keep the Trimix cold by returning the bottle to the refrigerator, or by placing the bottle in a cup of ice.

Step 2:  PREPARE THE SYRINGE

a. Wipe the rubber top of the vial with an alcohol pad.

b. After removing the cap of the needle, pull the plunger back to the desired dosage, filling this volume with air. Use a new needle and syringe each time.

c. Insert the needle through the rubber top and inject the air into the vial.

d. Turn the vial with needle and syringe inserted upside down. Pull back on the syringe plunger in a slow and steady motion until the desired dosage is achieved.

e. Tap the side of the syringe (1cc tuberculin syringe with a 29 gauge needle) to allow any air bubbles to float towards the needle. Avoid having these air bubbles in the syringe when self-injecting by first injecting out the collected bubbles that may form.

f. Remove the needle from the bottle and replace the protective cap on the needle.

Step 3: SELECT AND PREPARE THE SITE FOR INJECTION

a. The proper location for injection is at the 9-11 and 1-3 o'clock positions, between the base and mid-portion of the penis.(see diagram) Avoid the midline because of potential for injury to the urethra (6 o'clock; for urinary passage) and the penile arteries and nerves (near 12 o'clock). Avoid any visible veins or arteries on the surface.

b. Grasp and pull the head of the penis toward the side of your leg with the index finger and thumb (use the left hand, if right handed). While maintaining light tension, select a site for injection.

c. Clean the site with an alcohol pad.

Step 4: INJECT TRIMIX AND APPLY COMPRESSION         

a. With a steady and continuous motion, penetrate the skin with the needle at a 90 o angle. The needle should then be advanced to the hub. Slight resistance is encountered as the needle passes into the proper position within the erectile tissue (corporeal body).

b. Inject the Trimix over approximately 4 seconds. Withdraw the needle from the penis and apply compression to the injection site for approximately 1 minute. Several minutes of compression may be required to avoid bleeding, especially if you are an aspirin user.

c. Replace the cap on the needle and dispose of properly.

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