Botox: Botulinum toxin. Botulinum toxin (BTX) is a neurotoxic protein produced by the bacterium Clostridium botulinum and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction and thus causes flaccid paralysis.
The battle against wrinkles has lasted for centuries. But when the FDA approved Botox for cosmetic use in 2002, it forever changed the anti-aging market.
Botox used to be for boomers, but not anymore. Increasingly younger women are embracing the injections that promise to smooth out wrinkles and result in a more youthful appearance.
Millennials and Gen Xers are heading to physicians not to undo the toll years have taken on their skin, but to prevent it.
Facts of Botox:
- Botox is the most popular non-surgical cosmetic treatment, with more than 6 million Botox treatments administered each year.
- Botox is a neurotoxin derived from Clostridium botulinum, an organism found in the natural environment where it is largely inactive and non-toxic.
- Botox is used to reduce fine lines and wrinkles by paralyzing the underlying muscles.
- People also use Botox to treat migraines, excess sweating, muscular disorders, and some bladder and bowel disorders.
- Just 1 gram of botulinum toxin could kill over 1 million people. Two kilograms could kill the entire human population of Earth.
- Botox blocks signals from the nerves to the muscles. The injected muscle can no longer contract, which causes the wrinkles to relax and soften. It is most often used on forehead lines, crow's feet (lines around the eye) and frown lines. Wrinkles caused by sun damage and gravity will not respond to Botox.
- Botox is safe to use long term, and you can stop using it at any time without your skin looking worse than it did before you started Botox. When used for cosmetic purposes, medical insurance does not cover Botox treatments. Botox injections use forms of botulinum toxin to paralyze muscle activity temporarily.
- Getting Botox takes only a few minutes and doesn't require anesthesia. Botox is injected with a fine needle into specific muscles with only minor discomfort. It generally takes three to seven days to take full effect, and it is best to avoid alcohol starting at least one week before the procedure.
- Athlete's metabolism runs at a much higher rate than most people. Physically active bodies tend to heal faster and will eliminate the Botox from their body more quickly. ... Through repeated Botox injections, your specific facial muscles become conditioned, and the results will start to last longer.
- When some people see their wrinkles form again after the rejuvenating effects of Botox wear off, they assume that the treatment made their wrinkles worse. ... In fact, regular Botox use can actually retrain certain muscles to move less, leading to smoother skin with less Botox over time.
- It is possible for Botox to result in a lower ability to move the muscles on the face. ... A trained professional should be able to inject the Botox only into the muscles that directly cause the wrinkles. Avoiding muscles such as those needed for smiling is imperative.
Botox is currently approved for the following therapeutic applications:
- Blepharospasm (spasm of the eyelids).
- Idiopathic rotational cervical dystonia (severe neck and shoulder muscle spasms).
- Chronic migraine.
- Severe primary axillary hyperhidrosis (excessive sweating).
- Strabismus (crossed eyes).
- Post stoke upper limb spasticity
- Detrusor (bladder wall muscle) overactivity -causing urinary incontinence.
- Overactive bladder.
- Hemifacial spasm.
- Glabellar lines (frown lines between the eyebrows).
- Canthal lines (crow's feet).
Botox is also used off-label (not approved) for:
- Achalasia (an issue with the throat that makes swallowing difficult).
- Anal fissure and anismus (dysfunction of the anal sphincter).
- Sialorrhea (producing too much saliva).
- Allergic rhinitis.
- Sphincter of oddi (hepatopancreatic) dysfunction (causes abdominal pain).
- Cerebral Palsy.
- Oromandibular dystonia (forceful contraction of the jaw, face, and/or tongue).
- Laryngeal dystonia (forceful contraction of the vocal cords).
Possible side effects may include:
Injections with botulinum toxin are generally well tolerated and there are few side effects. In rare cases, an individual may have a genetic predisposition that results in a mild, transient unusual response to the drug.
Around 1% people receiving injections of botulinum toxin type A develop antibodies to the toxin that make subsequent treatments ineffective.
- muscle weakness near where the medicine was injected;
- trouble swallowing for several months after treatment;
- muscle stiffness, neck pain, pain in your arms or legs;
- blurred vision, puffy eyelids, dry eyes, drooping eyebrows;
- dry mouth;
- headache, tiredness;
Getting Botox takes only a few minutes and doesn't require anesthesia. Botox is injected with a fine needle into specific muscles with only minor discomfort.
Botox results will not appear instantly. It takes 5 to 7 days before the effects of Botox start to work and for you to start to see a reduction in the lines and wrinkles on the face. It takes 2 weeks to see the full expression of the treatment with Botox that you get.
And it is best to avoid alcohol starting at least one week before the procedure.
Typically, the effects of Botox last for up to three to four months. Therefore, the recommended treatment is once every three to four months.
Nevertheless, if your facial muscles begin to train themselves to contract less, the period of time for each treatment may be extended longer than three or four months.
- Frown lines wrinkle reduction
- Forehead lines wrinkle reduction
- Crow’s feet lines reduction
- Masseter muscle reduction (jaw line muscle) for slim jaw line
- TMJ pain reduction
- Trapezius muscle reduction for slim and smooth shoulder line
- Cervical paraspinal muscle and trapezius muscle injection for persistent neck/shoulder pain/chronic headache
- Calf muscle (gastrocnemius and soleus muscles) reduction
- Axillary injection for severe primary axillary hyperhidrosis (excessive sweating)
- Migraine headache,
- Tension headache
- Uncontrolled blinking (blepharospasm)
- Cervical dystonia(torticollis)